European Renal Cell Study Group

  

Main Program: 24.04.2021

 

 

 

 

 

 

 

 

 

08.15 - 08.30

 

Welcome:

Peter R. Mertens (Magdeburg, Germany)

 

 

 

 

Scientific Session 1   "Diabetic nephropathy"

Chairs: Paola Romagnani (Florence, Italy) / Josef Pfeilschifter (Frankfurt, Germany)

 

 

 

 

 

 

 

 

08.30 - 08.45

 

Short   communication: A01

"Endothelial Injury in Diabetic Nephropathy leads to Glomerular PLVAP Expression"

 

 

 

Elena E. Wolf  (Dresden, Germany)

 

 

 

 

 

 

08.45 - 09.00

 

Short communication: A02

"Long noncoding RNAs control the expression of HIF1A in an in-vitro model of   hyperglycemia and hypoxia"

 

 

 

Simone Reichelt-Wurm (Regensburg, Germany)

 

 

 

 

 

 

09.00 - 09.25

Mini Lecture: A03

"Intra-organ cross-talk via YB-1 in the kidney"

 

 

 

Berend Isermann (Leipzig, Germany)

 

 

 

 

09.25 - 09.50

Mini Lecture: A04

"The Proteasomal Degradation System Plays a Prominent Role in Glomerular Filtration Barrier Function"

Catherine Meyer-Schwesinger (Hamburg, Germany)

 

 

 

 

09.50 - 10.30

Coffee break

 

 

 

10.30 - 10.45

 

Short communication: A05

"Calpastatin prevents Angiotensin II-mediated podocyte injury through maintenance of autophagy"

Olivia Lenoir (Paris, France)

 

 

 

10.45 - 11.00

 

Short communication: A06

"The role of filamins in mechanically stressed podocytes"

Felix Kliewe   (Greifswald, Germany)

 

 

 

11.00 - 11.25

 

Mini Lecture: A07

"Super-resolution microscopy – a groundbreaking technology that will change kidney research and diagnostics"

 

 

 

 

Nicole Endlich (Greifswald, Germany)

 

 

 
                 

 

 

 

Scientific Session 2   "Renal diseases"

Chairs: Pierre Ronco (Paris, France) / Maja Lindenmeyer (Hamburg, Germany)

 

 

 

 

 

 

11.25 - 11.50

Mini Lecture: B01

"Why is the DOCA-salt model efficacious to   induce FSGS? Identification of a targetable pathway to prevent recruitment of   glomerular parietal cells"

Pierre-Louis   Tharaux (Paris, France)

 

 

11.50 - 12.05

 

 

 

 

12.05 - 12.30

 

Short communication: B02

"High salt dependent kidney damage accompanied glucosuria/proteinuria is prevented   by Ybx1 deletion"

Anja Bernhardt (Magdeburg, Germany)

 

Mini Lecture: B03

"Lymphangiogenesis ameliorates rejection of renal transplants"

 

 

Dontscho Kerjaschki (Vienna, Austria)

 

 

 

 

 

 

 

 

12.30 - 12.55

Mini Lecture: B04

"COVID and Kidney"

Tobias Huber (Hamburg, Germany)

 

 

 

 

13.00 - 14.00

 

Lunch break

 

 

 

 

 

 

 

 

Scientific Session 3 "AKI - Tubular cells"

Chairs: Nicole Endlich (Greifswald, Germany) / Christian Kurts (Bonn, Germany)

 

 

 

 

 

 

14.00 - 14.25

Mini Lecture: C01

"Tubular injury and recovery"

 

 

Paola Romagnani (Florence, Italy)

 

 

 

 

 

 

 

14.25 - 14.40

Short communication: C02

"Asymptomatic hyperuricemia acts as antioxidant during acute kidney injury and disease"

Stefanie Steiger (Munich, Germany)

 

 

 

 

 

 

 

14.40 - 15.05

Mini Lecture: C03

"Human Kidney Tubuloids"

 

 

Fjodor Yousef Yengej (Utrecht, Netherlands)

 

 

 

 

 

 

 

 

15.05 - 15.20

Short communication: C04

"Deletion of cold shock protein DbpA protects against acute kidney injury"

Charlotte Reichardt (Magdeburg, Germany)

 

 

 

15.20 - 15.35

Short communication: C05

"Pathophysiological role of kidney tubular Desmoglein-2"

Tong Xu (Aachen, Germany)

 

 

 

15.35 - 16.00

Coffee break

 

 

 

 

 

 

16:00 – 16.15

Short communication: C06

 

 

 

"A kidney-on-the-chip approach using primary human tubular cells in a 3D co-culture system"

 

 

 

Julien Marschner (Munich, Germany)

 

 

 

 

 

 

16.15 - 16.30

Short communication: C07

 

 

 

"The role of indoleamine 2,3-dioxygenase in ischemia-reperfusion injury of renal tubular epithelial cells"

 

 

 

Theodoros Eleftheriadis (Larissa, Greece)

 

 

 

 

 

 

 

Scientific Session 4 "Combining Forces"

Chairs: Peter Mertens (Magdeburg, Germany) / Ute Raffetseder (Aachen, Germany)

 

 

 

 

 

16.30 - 16.55

Mini Lecture: D01

"ERCSG cDNA BioBank"

 

 

Maja Lindenmeyer (Hamburg, Germany)

 

 

 

 

 

 

16.55 - 17.20

Mini Lecture: D02

"Crystal clots as therapeutic target in cholesterol crystal embolism-related acute kidney infarction and failure"

Hans-Joachim Anders (Munich, Germany) 

 

 

 

 

17.20 - 17.35

Short communication: D03

"The renal function of Lipoprotein Receptor-Related Proteins other than LRP2"

 

 

Tilman Jobst-Schwan (Erlangen, Germany)

 

 

 

 

 

 

 

Scientific Session 5   "Glomerular cells"

Chairs: Pierre-Louis   Tharaux (Paris, France)/ Berend Isermann (Leipzig, Germany)

 

 

 

 

 

 

 

 

17.35 - 17.50

Short communication: E01

"Protein  4.1O links Polycystin-1 to the actin cytoskeleton and silences the   cystogenesis through inhibition of Hippo signaling"

Lorenz Sellin (Düsseldorf, Germany)

 

 

17.50 - 18.05

Short communication: E02

"Deep-learning  enabled spatial quantification of single-cell transcripts, super-resolved correlative podocyte foot process morphology and glomerular morphometry in routine kidney biopsy specimen"

 

 

Florian Siegerist (Greifswald, Germany)

 

 

 

 

 

 

18.05 - 18.20

Short communication: E03

"PDGFR-β and its ligands in focal segmental glomerulosclerosis (FSGS)"

Ting Jia (Aachen, Germany) 

 

18.20 - 18.35

Short communication: E04

"Interplay of biglycan with its receptors in inflammation and autophagy"

Liliana Schaefer (Frankfurt, Germany)

 

 

 

 

18.35 - 18.50

Short communication: E05

"Enhanced LPS-induced inflammation is dependent on intracellular YB‑1"

 Lukas Amann (Magdeburg, Germany)

 

 

   

 

 

 

Scientific Session 6   "Renal fibrosis"

Chairs: Michael Zeisberg (Göttingen, Germany)/ Miriam Banas (Regensburg, Germany)

 

 

 

 

18.50 - 19.05

Mini Lecture: F01

"Cold shock proteins in health and (kidney) disease"

Ute Raffetseder (Aachen, Germany)

 

 

 

                   

 

19.05 - 19.20

Short communication: F02

"Fibrosis and immune cell infiltration are separate events regulated by cell-specific   Notch3 expression"

Sabine Brandt (Magdeburg, Germany)

 

 

 

19.20 - 19.35

 

Short communication: F03

"Relevance of intracellular signaling pathways in resident PDGFRß+ cells for the   development of kidney fibrosis"

Armin Kurtz (Regensburg, Germany)

 

 

 

 

 

 

 

19.35 - 19.50

Short communication: F04

"CCN2 aggravates acute DNA damage and the subsequent   DDR-Senescence-Fibrosis sequence following renal IRI”

 

 

 

Floris Valentijn (Utrecht, Netherlands)

 

 

 

 

 

 

19.50 - 20.05

Short communication: F05

"Renal denervation exacerbates LPS- and antibody-induced acute kidney injury, but protects from pyelonephritis”

 

 

Alex Böhner (Bonn, Germany)

 

 

 

 

20.05 - 20.15

Short communication: F06

"PP2A Phosphatase Inhibition is Anti-Fibrotic through Ser77 Phosphorylation-mediated ARNT/ARNT Homodimer Formation"

 

 

Michael Zeisberg (Göttingen, Germany)

 

 

 

 

20.15 - 20.30

ERCSG Business Meeting

Chaired by Malcolm Davies

 

 

 

THE END

 

 

 

 

 

 

 

                     

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